After transferring from film school, she continued her education at San Francisco State University, where she majored in film and minored in art. Murphy-Hashiguchi graduated with a bachelor of arts degree in animation.
Prior to her career in animation, she worked for Federal Express during a six year period. Beginning her career in the early 1990s, Murphy-Hashiguchi assistant animated the original Rugrats theme song, used from 1991 to 2000. She served as supervising director on The Grim Adventures of Billy & Mandy, timing director on The Simpsons and an animation timer for American Dad!.
Murphy-Hashiguchi has been nominated for four Emmy Awards, twice for her work on SpongeBob SquarePants as a sheet timer, and once each for sheet timing on The Powerpuff Girls as well as directing on Chowder.
- 6th Grade Girls
- Eugene's Bike
- Gerald Comes Over
- Harold's Bar Mitzvah
- Haunted Train
- Helga's Makeover
- Magic Show
- Part Time Friends
- Partners (credited as "Julie" in the opening credits)
- Stoop Kid
- Tour de Pond (credited as "Julie" in the opening credits)
- Wheezin' Ed